Diseases (114)
Diagnostic Testing (45)

Note:

Note:

Rule out iron liver disease.


Note:

Rule out iron deficiency.


Note:

Evaluate for possible iron deficiency secondary to achlorhydria. Especially if anemia is present.


Note:

Rule out liver disease due to iron overload, hemochromatosis.


Note:

If anemia is present, esp. if microcytic/hypochromic.


Note:

Rule out hemochromatosis.


Note:

Note:

Rule out hemochromatosis.


Note:

If patient is diagnosed with folate or Vit. B12 deficiency but the MCV is normal or low


Note:

To rule out hemochromatosis


Note:

Rule out iron load, hemochromatosis.


Note:

Rule out iron deficiency anemia.


Note:

Rule out hemochromatosis.


Note:

If anemia present.


Note:

To evaluate and monitor anemia.

Disease Management Testing (23)

Note:

To monitor iron related therapy in iron related deficiency anemia.


Note:

If patient has been previously shown to have concommitant iron deficiency


Note:

If anemia is seen.


Note:

Rule out iron deficiency if anemia is present.


Note:

If chronic liver disease cased by iron overload.


Note:

If abnormally low?


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due anemia.


Note:

If hemoglobin is low due to anemia.

Other Supportive/Alternative Tests (43)

Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

I hemoglobin is low.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.


Note:

If hemoglobin is low due to anemia.

Overview

Iron is a structural part of hemoglobin, which functions to transport oxygen. Ingested iron is mainly absorbed in the form of Fe2 + in the duodenum and upper jejunum. Absorbed iron is then transported in blood plasma by transferrin-iron complexes. A maximum of 2 Fe2 + ions per transferrin molecule can be transported. Serum iron is almost completely bound to transferrin.

Testing for iron (non-heme) levels is used in the diagnosis and treatment of diseases such as iron deficiency anemia and hemochromatosis. Hemochromatosis is a disease associated with iron deposits in tissues, usually deposited in the form of iron-containing pigments such as hemosiderin and hemofuscin. Disease is characterized by pigmentation of the skin and chronic renal disease. In addition, iron testing can be useful in the diagnosis and monitoring of microcytic anemias (e.g. due to iron metabolism disorders and hemoglobinopathies), macrocytic anemias (e.g. due to vitamin B12 deficiency, folic acid deficiency, and drug-induced metabolic disorders of unknown origin), normocytic anemias such as anemia of chronic renal disease (erythropoetin deficiency), hemolytic anemia, bone marrow disease, and toxic bone marrow damage. Percent iron saturation should also be obtained because it is more helpful than serum iron in estimating iron stores and evaluating for iron deficiency anemia.

Clinical Utility

  • Differential diagnosis of anemia, especially with hypochromia and/or low red blood cell MCV
  • As an aid in diagnosis of thalassemia and sideroblastic anemia
  • As an aid in diagnosis of hemochromatosis
  • Diagnosis of iron deficiency

Interpretation

Increased in:

  • Hemosiderosis due to increased iron uptake
  • Multiple transfusions
  • Hemolytic anemia
  • Pernicious anemia
  • Aplastic or hypoplastic anemia
  • Viral hepatitis
  • Lead poisoning
  • Thalassemias
  • Some drugs: estrogens, ethanol, oral contraceptives

Decreased in:

  • Iron deficiency
  • Nephrotic syndrome
  • Chronic renal failure
  • Many infections
  • Active hematopoiesis
  • Remission of pernicious anemia
  • Some malignancies (some carcinomas)
  • Gastrectomy
  • Nutritional (children and premenopausal women)
  • Pregnancy
  • Chronic blood loss due to bleeding

Reference Ranges

Units: mcg/dL / umol/L
Newborn: 100-250 / 17.9-44.8
Infant: 40-100 / 7.2-17.9
Child: 50-120 / 9.0-21.5
Intoxicated child: 280-2550 / 50.1-456.5
Fatally poisoned child: 1800 / 322.2
Adult M: 65-175 / 11.6-31.3
Adult F: 50-170 / 9.0-30.4

Methodology

Timed Endpoint Spectroscopy Method.

Specimen Collection

Serum (SST) or Plasma Heparin (Green)

Draw blood before other specimens that require anticoagulated tubes. Reject hemolyzed samples.

Stability:

  • Ambient: 14 days
  • Refrigerated: 14 days
  • Frozen: 28 days
  • Separate serum of Plasma within 45 minutes of collection.

Additional Testing

Complete Blood Count with RBC Indices, Vitamin B12, Folate, Ferritin, TIBC, Transferrin, Transferrin Receptor, Erythropoietin, Hemochromatosis Mutation, Lead Level, Occult Blood, Porphyrins Urine.

CPT
83540$6.47

ICD10
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Showing results for all states.
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ICD10 CODE AND DESCRIPTIONLCD CODENCD CODE
A51.32 - Syphilitic alopecia
B15 - Acute hepatitis A
B16 - Acute hepatitis B
B16.1 - Acute hepatitis B with delta-agent without hepatic coma
B17 - Other acute viral hepatitis
B17.1 - Acute hepatitis C
B17.10 - Acute hepatitis C without hepatic coma
B17.2 - Acute hepatitis E
B18 - Chronic viral hepatitis
B18.0 - Chronic viral hepatitis B with delta-agent
B18.1 - Chronic viral hepatitis B without delta-agent
B18.2 - Chronic viral hepatitis C
B18.8 - Other chronic viral hepatitis
B18.9 - Chronic viral hepatitis, unspecified
B19 - Unspecified viral hepatitis
B19.2 - Unspecified viral hepatitis C
B19.20 - Unspecified viral hepatitis C without hepatic coma
B19.21 - Unspecified viral hepatitis C with hepatic coma
B25.1 - Cytomegaloviral hepatitis
B26.81 - Mumps hepatitis
B58.1 - Toxoplasma hepatitis
C00 - Malignant neoplasm of lip
C00.9 - Malignant neoplasm of lip, unspecified
C01 - Malignant neoplasm of base of tongue
C02 - Malignant neoplasm of other and unspecified parts of tongue
C02.9 - Malignant neoplasm of tongue, unspecified
C03 - Malignant neoplasm of gum
C03.0 - Malignant neoplasm of upper gum
C03.1 - Malignant neoplasm of lower gum
C03.9 - Malignant neoplasm of gum, unspecified
C04.9 - Malignant neoplasm of floor of mouth, unspecified
C05 - Malignant neoplasm of palate
C05.9 - Malignant neoplasm of palate, unspecified
C06.0 - Malignant neoplasm of cheek mucosa
C06.9 - Malignant neoplasm of mouth, unspecified
C07 - Malignant neoplasm of parotid gland
C08 - Malignant neoplasm of other and unspecified major salivary glands
C08.0 - Malignant neoplasm of submandibular gland
C08.1 - Malignant neoplasm of sublingual gland
C08.9 - Malignant neoplasm of major salivary gland, unspecified
C09 - Malignant neoplasm of tonsil
C09.9 - Malignant neoplasm of tonsil, unspecified
C10 - Malignant neoplasm of oropharynx
C10.9 - Malignant neoplasm of oropharynx, unspecified
C11 - Malignant neoplasm of nasopharynx
C11.9 - Malignant neoplasm of nasopharynx, unspecified
C12 - Malignant neoplasm of pyriform sinus
C13 - Malignant neoplasm of hypopharynx
C14 - Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
C15 - Malignant neoplasm of esophagus

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  • AK - Alaska
  • AL - Alabama
  • AR - Arkansas
  • AS - American Samoa
  • AZ - Arizona
  • CA - California - Entire State
  • CO - Colorado
  • CT - Connecticut
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  • GA - Georgia
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  • MN - Minnesota
  • MO - Missouri - Entire State
  • MS - Mississippi
  • MT - Montana
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  • ND - North Dakota
  • NE - Nebraska
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  • PR - Puerto Rico
  • RI - Rhode Island
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  • TN - Tennessee
  • TX - Texas
  • UT - Utah
  • VA - Virginia
  • VI - Virgin Islands
  • VT - Vermont
  • WA - Washington
  • WI - Wisconsin
  • WV - West Virginia
  • WY - Wyoming
  • CNMI - Northern Mariana Islands
  • EM - Missouri - Northeastern & Southern
  • WM - Missouri - Northwestern
  • DN - New York - Downstate
  • QN - New York - Queens
  • UN - New York - Upstate
  • NF - California - Northern
  • SF - California - Southern
Showing results for all states.
Filter:
ICD10 CODE AND DESCRIPTIONLCD CODENCD CODE
A51.45 - Secondary syphilitic hepatitis
B00.81 - Herpesviral hepatitis
B15.0 - Hepatitis A with hepatic coma
B15.9 - Hepatitis A without hepatic coma
B16.0 - Acute hepatitis B with delta-agent with hepatic coma
B16.1 - Acute hepatitis B with delta-agent without hepatic coma
B16.2 - Acute hepatitis B without delta-agent with hepatic coma
B16.9 - Acute hepatitis B without delta-agent and without hepatic coma
B17.0 - Acute delta-(super) infection of hepatitis B carrier
B17.1 - Acute hepatitis C
B17.10 - Acute hepatitis C without hepatic coma
B17.11 - Acute hepatitis C with hepatic coma
B17.2 - Acute hepatitis E
B17.8 - Other specified acute viral hepatitis
B17.9 - Acute viral hepatitis, unspecified
B18.0 - Chronic viral hepatitis B with delta-agent
B18.1 - Chronic viral hepatitis B without delta-agent
B18.2 - Chronic viral hepatitis C
B18.8 - Other chronic viral hepatitis
B18.9 - Chronic viral hepatitis, unspecified
B19.0 - Unspecified viral hepatitis with hepatic coma
B19.1 - Unspecified viral hepatitis B
B19.10 - Unspecified viral hepatitis B without hepatic coma
B19.11 - Unspecified viral hepatitis B with hepatic coma
B19.2 - Unspecified viral hepatitis C
B19.20 - Unspecified viral hepatitis C without hepatic coma
B19.21 - Unspecified viral hepatitis C with hepatic coma
B19.9 - Unspecified viral hepatitis without hepatic coma
B25.1 - Cytomegaloviral hepatitis
B26.81 - Mumps hepatitis
B58.1 - Toxoplasma hepatitis
B94.2 - Sequelae of viral hepatitis
C00.0 - Malignant neoplasm of external upper lip
C00.1 - Malignant neoplasm of external lower lip
C00.2 - Malignant neoplasm of external lip, unspecified
C00.3 - Malignant neoplasm of upper lip, inner aspect
C00.4 - Malignant neoplasm of lower lip, inner aspect
C00.5 - Malignant neoplasm of lip, unspecified, inner aspect
C00.6 - Malignant neoplasm of commissure of lip, unspecified
C00.8 - Malignant neoplasm of overlapping sites of lip
C00.9 - Malignant neoplasm of lip, unspecified
C02.0 - Malignant neoplasm of dorsal surface of tongue
C02.1 - Malignant neoplasm of border of tongue
C02.2 - Malignant neoplasm of ventral surface of tongue
C02.3 - Malignant neoplasm of anterior two-thirds of tongue, part unspecified
C02.4 - Malignant neoplasm of lingual tonsil
C02.8 - Malignant neoplasm of overlapping sites of tongue
C02.9 - Malignant neoplasm of tongue, unspecified
C03.0 - Malignant neoplasm of upper gum
C03.1 - Malignant neoplasm of lower gum

References