Abnormal in:

• Gout (uric acid)
• Pseudogout (calcium pyrophosphate deposition disease)
• Rheumatoid arthritis
• Infectious arthritis (lactate dehydrogenase)
• Immune-based arthritis
• Bacterial infection (protein)
• Joint injury
• Lower than normal viscocity is associated with inflammation
• Decreased clarity (cloudy SF) may indicate crystals, WBCs, or microorganisms in the fluid
• Reddish SF indicates red blood cells in the fluid which can indicate bleeding disorders
• Decreased glucose is associated with inflammation but compare with serum glucose