Diseases (204)
Diagnostic Testing (119)

Note:

Rule out thyroid disorders.


Note:

Note:

Evaluate for thyroid disorders


Note:

Note:

Rule out thyroid disease.


Note:

Rule out thyroid disease.


Note:

Note:

Rule out thyroid disease.


Note:

Note:

Rule out secondary cause of hypercholesterolemia.


Note:

Evaluate for hypothyroidism


Note:

Evaluate for possible hyperthyroidism.


Note:

Rule out secondary cause of hypercholesterolemia.


Note:

Rule out autoimmune thyroid disease.


Note:

If symptoms of hypo-or hyperthyroidism are present.


Note:

Note:

Rule out thyroid disorders.


Note:

Rule out thyroid disease.


Note:

Rule out hypothyroidism.


Note:

Rule out thyroid disease as etiology of osteoporosis.


Note:

Rule out hypothyroidism.


Note:

Rule out Hypothyroidism.


Note:

Rule out thyroid disease.


Note:

Rule out thyroid disease if symptoms of thyroid diseases are present.


Note:

R/O hyperthyroidism


Note:

Rule out thyroid disease.


Note:

Rule out anemia due to hypothyroidism.


Note:

Rule out thyroid related diseases.


Note:

Rule out hypothyroidism.


Note:

Rule out thyroid related diseases.


Note:

R/O hypothyroidism as a cause of secondary hypertension


Note:

If genetic testing for HD is negative test to rule out thyroid disorders.


Note:

Note:

Rule out thyroid disease.


Note:

Rule out thyroid diseases.


Note:

Rule out thyroid diseases.


Note:

R/O Hypothyroidism


Note:

Rule out thyroid disease.


Note:

Rule out thyroid disease.


Note:

Rule out hypothyroidism.

Overview

Thyroid stimulating hormone (TSH) is a glycoprotein hormone produced by the anterior pituitary gland, which stimulates the thyroid gland to produce thyroid hormones. Secretion is stimulated by thyroid-releasing hormone from the hypothalamus. Free thyroid hormones (FT4 and FT3) work in a negative feedback loop to regulate the amount of TSH that is released from the pituitary gland. Dysregulation of TSH may either be a primary or secondary condition causing either hypo- or hyperthyroidism. Although thyroid issues are seen at all ages, onset is usually seen in the late 40s or early 50s, and affects females almost four times more often than males. An elevated TSH result usually means an underactive thyroid (hypothyroidism), whereas a decreased result means an overactive thyroid gland (hyperthyroidism) or excessive amounts of thyroid medication in an individual being treated for hypothyroidism. Measurement of serum TSH is the best initial laboratory test of thyroid function. If TSH levels are abnormal, free thyroxine (FT3) should then be measured. Also, measurement of anti-thyroperoxidase antibody should be done if the TSH level is high.

Clinical Utility

  • Screening for Thyroid Dysfunction
  • Diagnosis of Hyperthyroidism (Decreased TSH)
  • Diagnosis of Hypothyroidism (Elevated TSH)
  • Monitoring thyroid hormone replacement therapy
  • Monitoring anti-thyroid therapy (in hyperthyroidism)
  • Monitoring thyroid cancer patients taking thyroxine

Interpretation

Increased in:

  • Primary Hypothyroidism
  • Mild increase in subclinical hypothyroidism, which is defined as a mild increase in serum TSH and normal free thyroxine and triiodothyronine levels
  • Hashimoto's thyroiditis patients who are euthyroid
  • Ectopic TSH secretion in certain cancers (lung, breast).
  • Recovery phase of subacute thyroiditis
  • Recovery phase of a non-thyroidal illness
  • Thyroid hormone resistance

Decreased in:

  • Primary Hyperthyroidism
  • Secondary (pituitary) hypothyroidism
  • Tertiary hypothyroidism
  • Graves disease
  • Thyroiditis
  • Toxic adenomas
  • Acute medical or surgical illness
  • Some drugs such as dopamine
  • High-dose corticosteroids
  • Mild decrease in subclinical hyperthyroidism (mild decrease in serum TSH and normal free thyroxine and triiodothyronine levels, as in treated Graves disease, toxic multinodular goiter, autonomous thyroid hormone secretion, exogenous thyroid hormone therapy)
  • Euthyroid sick syndrome

Reference Ranges

  uU/mL mU/L
Premature infants    
(28-36 wk gestation): 0.7-27 0.7-27
1-4 days: 1.0-39 1.0-39
2-20 wk: 1.7-9.1 1.7-9.1
5 mo-20 yr: 0.7-6.4 0.7-6.4
Adults    
21-54 yr: 0.4-4.2 0.4-4.2
55-87 yr: 0.5-8.9 0.5-8.9
Pregnancy    
First trimester: 0.3-4.5 0.3-4.5
Second trimester: 0.5-4.6 0.5-4.6
Third trimester: 0.8-5.2 0.8-5.2


 

 

 

Methodology

Immunoassay.

Specimen Collection

Serum (SST)

Stability:

  • Ambient: 5 days
  • Refrigerated: 7 days
  • Frozen: 2 months

Additional Testing

Free Thyroxine (Free T4), Total Thyroxine (T4 total), Thyroid stimulating immunoglobulin, Thyroid peroxidase antibody (TPO antibody), Thyroid Stimulating Hormone Receptor Antibody, Thyroglobulin Antibody.

CPT
84436$6.87
84439$9.02
84443$16.8$16.8
84479$6.47

ICD10
  • AK - Alaska
  • AL - Alabama
  • AR - Arkansas
  • AS - American Samoa
  • AZ - Arizona
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  • WI - Wisconsin
  • WV - West Virginia
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  • CNMI - Northern Mariana Islands
  • EM - Missouri - Northeastern & Southern
  • WM - Missouri - Northwestern
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  • QN - New York - Queens
  • UN - New York - Upstate
  • NF - California - Northern
  • SF - California - Southern
Showing results for all states.
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ICD10 CODE AND DESCRIPTIONLCD CODENCD CODE
A23 - Brucellosis
A35 - Other tetanus
A37 - Whooping cough
A37.0 - Whooping cough due to Bordetella pertussis
A51.32 - Syphilitic alopecia
B02 - Zoster [herpes zoster]
B02.23 - Postherpetic polyneuropathy
B17 - Other acute viral hepatitis
B17.1 - Acute hepatitis C
B18 - Chronic viral hepatitis
B18.2 - Chronic viral hepatitis C
B19 - Unspecified viral hepatitis
B19.2 - Unspecified viral hepatitis C
B19.20 - Unspecified viral hepatitis C without hepatic coma
B19.21 - Unspecified viral hepatitis C with hepatic coma
B82 - Unspecified intestinal parasitism
B89 - Unspecified parasitic disease
C15 - Malignant neoplasm of esophagus
C16 - Malignant neoplasm of stomach
C17 - Malignant neoplasm of small intestine
C17.0 - Malignant neoplasm of duodenum
C17.1 - Malignant neoplasm of jejunum
C17.2 - Malignant neoplasm of ileum
C18 - Malignant neoplasm of colon
C19 - Malignant neoplasm of rectosigmoid junction
C20 - Malignant neoplasm of rectum
C21 - Malignant neoplasm of anus and anal canal
C21.0 - Malignant neoplasm of anus, unspecified
C25 - Malignant neoplasm of pancreas
C25.4 - Malignant neoplasm of endocrine pancreas
C25.9 - Malignant neoplasm of pancreas, unspecified
C26.0 - Malignant neoplasm of intestinal tract, part unspecified
C26.9 - Malignant neoplasm of ill-defined sites within the digestive system
C44 - Other and unspecified malignant neoplasm of skin
C48 - Malignant neoplasm of retroperitoneum and peritoneum
C48.0 - Malignant neoplasm of retroperitoneum
C48.1 - Malignant neoplasm of specified parts of peritoneum
C48.2 - Malignant neoplasm of peritoneum, unspecified
C48.8 - Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum
C49 - Malignant neoplasm of other connective and soft tissue
C49.A - Gastrointestinal stromal tumor
C56 - Malignant neoplasm of ovary
C56.1 - Malignant neoplasm of right ovary
C56.2 - Malignant neoplasm of left ovary
C56.3 -
C56.9 - Malignant neoplasm of unspecified ovary
C58 - Malignant neoplasm of placenta
C64 - Malignant neoplasm of kidney, except renal pelvis
C64.1 - Malignant neoplasm of right kidney, except renal pelvis
C64.2 - Malignant neoplasm of left kidney, except renal pelvis

Additional ICD10
  • AK - Alaska
  • AL - Alabama
  • AR - Arkansas
  • AS - American Samoa
  • AZ - Arizona
  • CA - California - Entire State
  • CO - Colorado
  • CT - Connecticut
  • DC - District of Columbia
  • DE - Delaware
  • FL - Florida
  • GA - Georgia
  • GU - Guam
  • HI - Hawaii
  • IA - Iowa
  • ID - Idaho
  • IL - Illinois
  • IN - Indiana
  • KS - Kansas
  • KY - Kentucky
  • LA - Louisiana
  • MA - Massachusetts
  • MD - Maryland
  • ME - Maine
  • MI - Michigan
  • MN - Minnesota
  • MO - Missouri - Entire State
  • MS - Mississippi
  • MT - Montana
  • NC - North Carolina
  • ND - North Dakota
  • NE - Nebraska
  • NH - New Hampshire
  • NJ - New Jersey
  • NM - New Mexico
  • NV - Nevada
  • NY - New York - Entire State
  • OH - Ohio
  • OK - Oklahoma
  • OR - Oregon
  • PA - Pennsylvania
  • PR - Puerto Rico
  • RI - Rhode Island
  • SC - South Carolina
  • SD - South Dakota
  • TN - Tennessee
  • TX - Texas
  • UT - Utah
  • VA - Virginia
  • VI - Virgin Islands
  • VT - Vermont
  • WA - Washington
  • WI - Wisconsin
  • WV - West Virginia
  • WY - Wyoming
  • CNMI - Northern Mariana Islands
  • EM - Missouri - Northeastern & Southern
  • WM - Missouri - Northwestern
  • DN - New York - Downstate
  • QN - New York - Queens
  • UN - New York - Upstate
  • NF - California - Northern
  • SF - California - Southern
Showing results for all states.
Filter:
ICD10 CODE AND DESCRIPTIONLCD CODENCD CODE
A23.0 - Brucellosis due to Brucella melitensis
A23.1 - Brucellosis due to Brucella abortus
A23.2 - Brucellosis due to Brucella suis
A23.3 - Brucellosis due to Brucella canis
A23.8 - Other brucellosis
A23.9 - Brucellosis, unspecified
A36.81 - Diphtheritic cardiomyopathy
A37.0 - Whooping cough due to Bordetella pertussis
A37.00 - Whooping cough due to Bordetella pertussis without pneumonia
A37.01 - Whooping cough due to Bordetella pertussis with pneumonia
A37.1 - Whooping cough due to Bordetella parapertussis
A37.10 - Whooping cough due to Bordetella parapertussis without pneumonia
A37.11 - Whooping cough due to Bordetella parapertussis with pneumonia
A37.8 - Whooping cough due to other Bordetella species
A37.80 - Whooping cough due to other Bordetella species without pneumonia
A37.81 - Whooping cough due to other Bordetella species with pneumonia
A37.9 - Whooping cough, unspecified species
A37.90 - Whooping cough, unspecified species without pneumonia
A37.91 - Whooping cough, unspecified species with pneumonia
A51.45 - Secondary syphilitic hepatitis
B00.81 - Herpesviral hepatitis
B02.0 - Zoster encephalitis
B02.1 - Zoster meningitis
B02.2 - Zoster with other nervous system involvement
B02.21 - Postherpetic geniculate ganglionitis
B02.22 - Postherpetic trigeminal neuralgia
B02.23 - Postherpetic polyneuropathy
B02.24 - Postherpetic myelitis
B02.29 - Other postherpetic nervous system involvement
B02.3 - Zoster ocular disease
B02.30 - Zoster ocular disease, unspecified
B02.31 - Zoster conjunctivitis
B02.32 - Zoster iridocyclitis
B02.33 - Zoster keratitis
B02.34 - Zoster scleritis
B02.39 - Other herpes zoster eye disease
B02.7 - Disseminated zoster
B02.8 - Zoster with other complications
B02.9 - Zoster without complications
B17.0 - Acute delta-(super) infection of hepatitis B carrier
B17.1 - Acute hepatitis C
B17.10 - Acute hepatitis C without hepatic coma
B17.11 - Acute hepatitis C with hepatic coma
B17.2 - Acute hepatitis E
B17.8 - Other specified acute viral hepatitis
B17.9 - Acute viral hepatitis, unspecified
B18.0 - Chronic viral hepatitis B with delta-agent
B18.1 - Chronic viral hepatitis B without delta-agent
B18.2 - Chronic viral hepatitis C
B18.8 - Other chronic viral hepatitis

References

  • Am Fam Physician. 2005;72:623.[PMID:16127951]
  • Lancet. 2003 Aug 9;362(9382):459-68. [PMID:12927435]
  • Eur Rev Med Pharmacol Sci. 2009 Sep-Oct;13(5):341-9. [PMID:19961039]
  • Exp Clin Endocrinol Diabetes. 1998;106 Suppl 4:S29-33. [PMID:9867193]
  • Horm Res. 1996;45(3-5):142-7. [PMID:8964573]
  • Am Fam Physician. 2005;72:1517.[PMID:16273818]
  • Clin Chem. 2005;51:1480. [PMID:15961550]
  • Eur J Endocrinol. 2006;154:633. [PMID:16645008]
  • Alan Wu. Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders; 4 edition (June 13, 2006). ISBN-10: 0721679757