Overview

Parathyroid hormone (PTH) is a peptide produced by the parathyroid gland. PTH principally serves in the maintenance of calcium homeostasis; thus, assessment of PTH can be an important diagnostic aid for diagnosis of calcium metabolism disorders. In healthy individuals, PTH is secreted from the parathyroid gland as a negative feedback response to circulating calcium ion levels. The half-life of intact PTH is 2 to 5 minutes.

Hypercalcemia may be due to hyperparathyroidism, a group of conditions characterized by an overproduction of PTH. Hyperparathyroidism is separated into primary, secondary, and tertiary causes. Primary hyperparathyroidism is most frequently due to a parathyroid tumor (usually benign) that secretes PTH without feedback control, leading to hypercalcemia, kidney stones, calcium deposits in organs, and decalcification of bone. With primary hyperparathyroidism, patients will generally have high calcium and high PTH levels, while phosphate levels are often low.

Secondary hyperparathyroidism is usually due to kidney failure. In secondary hyperparathyroidism, patients will generally have high PTH levels and low or normal calcium levels. Sometimes, persons with secondary hyperparathyroidism develop high serum calcium and still have high PTH; this is sometimes called tertiary hyperparathyroidism.

Hypocalcemia may be due to hypoparathyroidism or a failure of the parathyroid gland to produce sufficient PTH. Hypoparathyroidism may be due to a variety of conditions and may be persistent, progressive, or transient. Causes include an autoimmune disorder, parathyroid damage or removal during surgery, a genetic condition, and severe illnesses. Affected patients will generally have low PTH levels and low calcium levels and will also have high phosphate levels.

Note: because of the physiological relationship of circulating calcium and PTH, it is always important to interpret PTH results in association with serum calcium.

Clinical Utility
  • Diagnosis of hypercalcemia due to primary hyperparathyroidism related to parathyroid tumors
  • Diagnosis hypercalcemia due to secondary hyperparathyroidism related to kidney disorders, malabsorption, and other calcium metabolic disorders
  • Diagnosis of hypocalcemia due to hypoparathyroidism related to autoimmune disorders, injuries, surgery, and other related disorders

Interpretation

Increased in:

  • Primary hyperparathyroidism
  • Secondary hyperparathyroidism due to renal disease
  • Pseudohypoparathyroidism, Types I and II
  • Pseudo-idiopathic Hypoparathyroidism
  • Rickets
  • Osteomalacia
  • Vitamin D deficiency
  • Some drugs: Anticonvulsants, furosemide, propofol, phosphates

Decreased in:

  • Hypercalcemic states other than primary hyperparathyroidism
  • Hypoparathyroidism
  • Parathyroidectomy
  • Thyroid Surgery, some
  • Autoimmune Hypoparathyroidism
  • Sarcoidosis
  • Hyperthyroidism
  • Hypomagnesemia
  • Malignancy with hypercalcemia
  • Nonparathyroid hypercalcemia

Reference Ranges
  pg/ml ng/L
C-terminal &    
midmolecule    
Serum    
1-16 yr:  51-217  51-217
Adults:  50-330  50-330
Plasma (EDTA):    
     
N-Terminal:    
Serum    
2-13 yr:  14-21  14-21
Adult: 8-24  8-24
Intact molecule:    
Serum    
Cord:     
2-20 yr: 9-52  9-52
Adults:  10-65  10-65
Plasma (EDTA): 1.0-5.0 pmol/L  


 

 

Methodology

Chemiluminescent enzyme-labeled immunometric assay, ELISA.

Specimen Collection

Serum (SST) or Plasma EDTA (Lavender)

Fasting morning specimen preferred.
Place on ice; refrigerate during centrifugation, and freeze immediately.

Stability:

  • Store Frozen at -20 to -70°C

Additional Testing

Comprehensive Metabolic Panel (see CMP for listed tests), Calcitonin, Albumin, Creatinine, Phosphorous, Calcium, Magnesium, Vitamin D-25-Hydroxy, Thyroid Stimulating Hormone, Ellsworth-Howard test.

CPT
83970$ 41.28

ICD10
C41Malignant neoplasm of bone and articular cartilage of other and unspecified sites
C41.9Malignant neoplasm of bone and articular cartilage, unspecified
C74Malignant neoplasm of adrenal gland
C74.0Malignant neoplasm of cortex of adrenal gland
C74.1Malignant neoplasm of medulla of adrenal gland
C74.9Malignant neoplasm of unspecified part of adrenal gland
C74.90Malignant neoplasm of unspecified part of unspecified adrenal gland
C74.91Malignant neoplasm of unspecified part of right adrenal gland
C74.92Malignant neoplasm of unspecified part of left adrenal gland
E04Other nontoxic goiter
E04.1Nontoxic single thyroid nodule
E04.2Nontoxic multinodular goiter
E05Thyrotoxicosis [hyperthyroidism]
E05.1Thyrotoxicosis with toxic single thyroid nodule
E05.2Thyrotoxicosis with toxic multinodular goiter
E25Adrenogenital disorders
E25.0Congenital adrenogenital disorders associated with enzyme deficiency
E25.8Other adrenogenital disorders
E25.9Adrenogenital disorder, unspecified
E55Vitamin D deficiency
E55.0Rickets, active
E55.9Vitamin D deficiency, unspecified
I10Essential (primary) hypertension
I95Hypotension
I95.0Idiopathic hypotension
I99Other and unspecified disorders of circulatory system
M35.4Diffuse (eosinophilic) fasciitis
M72.6Necrotizing fasciitis
M83Adult osteomalacia
M83.2Adult osteomalacia due to malabsorption
M83.5Other drug-induced osteomalacia in adults
M83.8Other adult osteomalacia
M83.9Adult osteomalacia, unspecified
M85.5Aneurysmal bone cyst
M85.50Aneurysmal bone cyst, unspecified site
M87Osteonecrosis
M89Other disorders of bone
Q78Other osteochondrodysplasias
Q78.2Osteopetrosis

Additional ICD10
C40.0Malignant neoplasm of scapula and long bones of upper limb
C40.00Malignant neoplasm of scapula and long bones of unspecified upper limb
C40.01Malignant neoplasm of scapula and long bones of right upper limb
C40.02Malignant neoplasm of scapula and long bones of left upper limb
C40.1Malignant neoplasm of short bones of upper limb
C40.10Malignant neoplasm of short bones of unspecified upper limb
C40.11Malignant neoplasm of short bones of right upper limb
C40.12Malignant neoplasm of short bones of left upper limb
C40.2Malignant neoplasm of long bones of lower limb
C40.20Malignant neoplasm of long bones of unspecified lower limb
C40.21Malignant neoplasm of long bones of right lower limb
C40.22Malignant neoplasm of long bones of left lower limb
C40.3Malignant neoplasm of short bones of lower limb
C40.30Malignant neoplasm of short bones of unspecified lower limb
C40.31Malignant neoplasm of short bones of right lower limb
C40.32Malignant neoplasm of short bones of left lower limb
C40.9Malignant neoplasm of unspecified bones and articular cartilage of limb
C40.90Malignant neoplasm of unspecified bones and articular cartilage of unspecified limb
C40.91Malignant neoplasm of unspecified bones and articular cartilage of right limb
C40.92Malignant neoplasm of unspecified bones and articular cartilage of left limb
C41.0Malignant neoplasm of bones of skull and face
C41.1Malignant neoplasm of mandible
C41.2Malignant neoplasm of vertebral column
C41.3Malignant neoplasm of ribs, sternum and clavicle
C41.4Malignant neoplasm of pelvic bones, sacrum and coccyx
C41.9Malignant neoplasm of bone and articular cartilage, unspecified
C74.0Malignant neoplasm of cortex of adrenal gland
C74.00Malignant neoplasm of cortex of unspecified adrenal gland
C74.01Malignant neoplasm of cortex of right adrenal gland
C74.02Malignant neoplasm of cortex of left adrenal gland
C74.1Malignant neoplasm of medulla of adrenal gland
C74.10Malignant neoplasm of medulla of unspecified adrenal gland
C74.11Malignant neoplasm of medulla of right adrenal gland
C74.12Malignant neoplasm of medulla of left adrenal gland
C74.9Malignant neoplasm of unspecified part of adrenal gland
C74.90Malignant neoplasm of unspecified part of unspecified adrenal gland
C74.91Malignant neoplasm of unspecified part of right adrenal gland
C74.92Malignant neoplasm of unspecified part of left adrenal gland
D16.0Benign neoplasm of scapula and long bones of upper limb
D16.00Benign neoplasm of scapula and long bones of unspecified upper limb
D16.01Benign neoplasm of scapula and long bones of right upper limb
D16.02Benign neoplasm of scapula and long bones of left upper limb
D16.1Benign neoplasm of short bones of upper limb
D16.10Benign neoplasm of short bones of unspecified upper limb
D16.11Benign neoplasm of short bones of right upper limb
D16.12Benign neoplasm of short bones of left upper limb
D16.2Benign neoplasm of long bones of lower limb
D16.20Benign neoplasm of long bones of unspecified lower limb
D16.21Benign neoplasm of long bones of right lower limb
D16.22Benign neoplasm of long bones of left lower limb
D16.3Benign neoplasm of short bones of lower limb
D16.30Benign neoplasm of short bones of unspecified lower limb
D16.31Benign neoplasm of short bones of right lower limb
D16.32Benign neoplasm of short bones of left lower limb
D16.4Benign neoplasm of bones of skull and face
D16.8Benign neoplasm of pelvic bones, sacrum and coccyx
E04.0Nontoxic diffuse goiter
E04.1Nontoxic single thyroid nodule
E04.2Nontoxic multinodular goiter
E04.8Other specified nontoxic goiter
E04.9Nontoxic goiter, unspecified
E05.0Thyrotoxicosis with diffuse goiter
E05.00Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
E05.01Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm
E05.1Thyrotoxicosis with toxic single thyroid nodule
E05.10Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
E05.11Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
E05.2Thyrotoxicosis with toxic multinodular goiter
E05.20Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
E05.21Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
E05.3Thyrotoxicosis from ectopic thyroid tissue
E05.30Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis or storm
E05.31Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis or storm
E05.4Thyrotoxicosis factitia
E05.40Thyrotoxicosis factitia without thyrotoxic crisis or storm
E05.41Thyrotoxicosis factitia with thyrotoxic crisis or storm
E05.8Other thyrotoxicosis
E05.80Other thyrotoxicosis without thyrotoxic crisis or storm
E05.81Other thyrotoxicosis with thyrotoxic crisis or storm
E05.9Thyrotoxicosis, unspecified
E05.90Thyrotoxicosis, unspecified without thyrotoxic crisis or storm
E05.91Thyrotoxicosis, unspecified with thyrotoxic crisis or storm
E25.0Congenital adrenogenital disorders associated with enzyme deficiency
E25.8Other adrenogenital disorders
E25.9Adrenogenital disorder, unspecified
E55.0Rickets, active
E55.9Vitamin D deficiency, unspecified
E64.3Sequelae of rickets
E83.32Hereditary vitamin D-dependent rickets (type 1) (type 2)
I95.0Idiopathic hypotension
I95.1Orthostatic hypotension
I95.2Hypotension due to drugs
I95.3Hypotension of hemodialysis
I95.8Other hypotension
I95.81Postprocedural hypotension
I95.89Other hypotension
I95.9Hypotension, unspecified
I99.8Other disorder of circulatory system
I99.9Unspecified disorder of circulatory system
M83.0Puerperal osteomalacia
M83.1Senile osteomalacia
M83.2Adult osteomalacia due to malabsorption
M83.3Adult osteomalacia due to malnutrition
M83.4Aluminum bone disease
M83.5Other drug-induced osteomalacia in adults
M83.8Other adult osteomalacia
M83.9Adult osteomalacia, unspecified
M85.5Aneurysmal bone cyst
M85.50Aneurysmal bone cyst, unspecified site
M85.51Aneurysmal bone cyst, shoulder
M85.511Aneurysmal bone cyst, right shoulder
M85.512Aneurysmal bone cyst, left shoulder
M85.519Aneurysmal bone cyst, unspecified shoulder
M85.52Aneurysmal bone cyst, upper arm
M85.521Aneurysmal bone cyst, right upper arm
M85.522Aneurysmal bone cyst, left upper arm
M85.529Aneurysmal bone cyst, unspecified upper arm
M85.53Aneurysmal bone cyst, forearm
M85.531Aneurysmal bone cyst, right forearm
M85.532Aneurysmal bone cyst, left forearm
M85.539Aneurysmal bone cyst, unspecified forearm
M85.54Aneurysmal bone cyst, hand
M85.541Aneurysmal bone cyst, right hand
M85.542Aneurysmal bone cyst, left hand
M85.549Aneurysmal bone cyst, unspecified hand
M85.55Aneurysmal bone cyst, thigh
M85.551Aneurysmal bone cyst, right thigh
M85.552Aneurysmal bone cyst, left thigh
M85.559Aneurysmal bone cyst, unspecified thigh
M85.56Aneurysmal bone cyst, lower leg
M85.561Aneurysmal bone cyst, right lower leg
M85.562Aneurysmal bone cyst, left lower leg
M85.569Aneurysmal bone cyst, unspecified lower leg
M85.57Aneurysmal bone cyst, ankle and foot
M85.571Aneurysmal bone cyst, right ankle and foot
M85.572Aneurysmal bone cyst, left ankle and foot
M85.579Aneurysmal bone cyst, unspecified ankle and foot
M85.58Aneurysmal bone cyst, other site
M85.59Aneurysmal bone cyst, multiple sites
M87.0Idiopathic aseptic necrosis of bone
M87.00Idiopathic aseptic necrosis of unspecified bone
M87.01Idiopathic aseptic necrosis of shoulder
M87.011Idiopathic aseptic necrosis of right shoulder
M87.012Idiopathic aseptic necrosis of left shoulder
M87.019Idiopathic aseptic necrosis of unspecified shoulder
M87.02Idiopathic aseptic necrosis of humerus
M87.021Idiopathic aseptic necrosis of right humerus
M87.022Idiopathic aseptic necrosis of left humerus
M87.029Idiopathic aseptic necrosis of unspecified humerus
M87.03Idiopathic aseptic necrosis of radius, ulna and carpus
M87.031Idiopathic aseptic necrosis of right radius
M87.032Idiopathic aseptic necrosis of left radius
M87.033Idiopathic aseptic necrosis of unspecified radius
M87.034Idiopathic aseptic necrosis of right ulna
M87.035Idiopathic aseptic necrosis of left ulna
M87.036Idiopathic aseptic necrosis of unspecified ulna
M87.037Idiopathic aseptic necrosis of right carpus
M87.038Idiopathic aseptic necrosis of left carpus
M87.039Idiopathic aseptic necrosis of unspecified carpus
M87.04Idiopathic aseptic necrosis of hand and fingers
M87.041Idiopathic aseptic necrosis of right hand
M87.042Idiopathic aseptic necrosis of left hand
M87.043Idiopathic aseptic necrosis of unspecified hand
M87.044Idiopathic aseptic necrosis of right finger(s)
M87.045Idiopathic aseptic necrosis of left finger(s)
M87.046Idiopathic aseptic necrosis of unspecified finger(s)
M87.05Idiopathic aseptic necrosis of pelvis and femur
M87.050Idiopathic aseptic necrosis of pelvis
M87.051Idiopathic aseptic necrosis of right femur
M87.052Idiopathic aseptic necrosis of left femur
M87.059Idiopathic aseptic necrosis of unspecified femur
M87.06Idiopathic aseptic necrosis of tibia and fibula
M87.061Idiopathic aseptic necrosis of right tibia
M87.062Idiopathic aseptic necrosis of left tibia
M87.063Idiopathic aseptic necrosis of unspecified tibia
M87.064Idiopathic aseptic necrosis of right fibula
M87.065Idiopathic aseptic necrosis of left fibula
M87.066Idiopathic aseptic necrosis of unspecified fibula
M87.07Idiopathic aseptic necrosis of ankle, foot and toes
M87.071Idiopathic aseptic necrosis of right ankle
M87.072Idiopathic aseptic necrosis of left ankle
M87.073Idiopathic aseptic necrosis of unspecified ankle
M87.074Idiopathic aseptic necrosis of right foot
M87.075Idiopathic aseptic necrosis of left foot
M87.076Idiopathic aseptic necrosis of unspecified foot
M87.077Idiopathic aseptic necrosis of right toe(s)
M87.078Idiopathic aseptic necrosis of left toe(s)
M87.079Idiopathic aseptic necrosis of unspecified toe(s)
M87.08Idiopathic aseptic necrosis of bone, other site
M87.09Idiopathic aseptic necrosis of bone, multiple sites
M87.1Osteonecrosis due to drugs
M87.10Osteonecrosis due to drugs, unspecified bone
M87.11Osteonecrosis due to drugs, shoulder
M87.111Osteonecrosis due to drugs, right shoulder
M87.112Osteonecrosis due to drugs, left shoulder
M87.119Osteonecrosis due to drugs, unspecified shoulder
M87.12Osteonecrosis due to drugs, humerus
M87.121Osteonecrosis due to drugs, right humerus
M87.122Osteonecrosis due to drugs, left humerus
M87.129Osteonecrosis due to drugs, unspecified humerus
M87.13Osteonecrosis due to drugs of radius, ulna and carpus
M87.131Osteonecrosis due to drugs of right radius
M87.132Osteonecrosis due to drugs of left radius
M87.133Osteonecrosis due to drugs of unspecified radius
M87.134Osteonecrosis due to drugs of right ulna
M87.135Osteonecrosis due to drugs of left ulna
M87.136Osteonecrosis due to drugs of unspecified ulna
M87.137Osteonecrosis due to drugs of right carpus
M87.138Osteonecrosis due to drugs of left carpus
M87.139Osteonecrosis due to drugs of unspecified carpus
M87.14Osteonecrosis due to drugs, hand and fingers
M87.141Osteonecrosis due to drugs, right hand
M87.142Osteonecrosis due to drugs, left hand
M87.143Osteonecrosis due to drugs, unspecified hand
M87.144Osteonecrosis due to drugs, right finger(s)
M87.145Osteonecrosis due to drugs, left finger(s)
M87.146Osteonecrosis due to drugs, unspecified finger(s)
M87.15Osteonecrosis due to drugs, pelvis and femur
M87.150Osteonecrosis due to drugs, pelvis
M87.151Osteonecrosis due to drugs, right femur
M87.152Osteonecrosis due to drugs, left femur
M87.159Osteonecrosis due to drugs, unspecified femur
M87.16Osteonecrosis due to drugs, tibia and fibula
M87.161Osteonecrosis due to drugs, right tibia
M87.162Osteonecrosis due to drugs, left tibia
M87.163Osteonecrosis due to drugs, unspecified tibia
M87.164Osteonecrosis due to drugs, right fibula
M87.165Osteonecrosis due to drugs, left fibula
M87.166Osteonecrosis due to drugs, unspecified fibula
M87.17Osteonecrosis due to drugs, ankle, foot and toes
M87.171Osteonecrosis due to drugs, right ankle
M87.172Osteonecrosis due to drugs, left ankle
M87.173Osteonecrosis due to drugs, unspecified ankle
M87.174Osteonecrosis due to drugs, right foot
M87.175Osteonecrosis due to drugs, left foot
M87.176Osteonecrosis due to drugs, unspecified foot
M87.177Osteonecrosis due to drugs, right toe(s)
M87.178Osteonecrosis due to drugs, left toe(s)
M87.179Osteonecrosis due to drugs, unspecified toe(s)
M87.18Osteonecrosis due to drugs, other site
M87.180Osteonecrosis due to drugs, jaw
M87.188Osteonecrosis due to drugs, other site
M87.19Osteonecrosis due to drugs, multiple sites
M87.2Osteonecrosis due to previous trauma
M87.20Osteonecrosis due to previous trauma, unspecified bone
M87.21Osteonecrosis due to previous trauma, shoulder
M87.211Osteonecrosis due to previous trauma, right shoulder
M87.212Osteonecrosis due to previous trauma, left shoulder
M87.219Osteonecrosis due to previous trauma, unspecified shoulder
M87.22Osteonecrosis due to previous trauma, humerus
M87.221Osteonecrosis due to previous trauma, right humerus
M87.222Osteonecrosis due to previous trauma, left humerus
M87.229Osteonecrosis due to previous trauma, unspecified humerus
M87.23Osteonecrosis due to previous trauma of radius, ulna and carpus
M87.231Osteonecrosis due to previous trauma of right radius
M87.232Osteonecrosis due to previous trauma of left radius
M87.233Osteonecrosis due to previous trauma of unspecified radius
M87.234Osteonecrosis due to previous trauma of right ulna
M87.235Osteonecrosis due to previous trauma of left ulna
M87.236Osteonecrosis due to previous trauma of unspecified ulna
M87.237Osteonecrosis due to previous trauma of right carpus
M87.238Osteonecrosis due to previous trauma of left carpus
M87.239Osteonecrosis due to previous trauma of unspecified carpus
M87.24Osteonecrosis due to previous trauma, hand and fingers
M87.241Osteonecrosis due to previous trauma, right hand
M87.242Osteonecrosis due to previous trauma, left hand
M87.243Osteonecrosis due to previous trauma, unspecified hand
M87.244Osteonecrosis due to previous trauma, right finger(s)
M87.245Osteonecrosis due to previous trauma, left finger(s)
M87.246Osteonecrosis due to previous trauma, unspecified finger(s)
M87.25Osteonecrosis due to previous trauma, pelvis and femur
M87.250Osteonecrosis due to previous trauma, pelvis
M87.251Osteonecrosis due to previous trauma, right femur
M87.252Osteonecrosis due to previous trauma, left femur
M87.256Osteonecrosis due to previous trauma, unspecified femur
M87.26Osteonecrosis due to previous trauma, tibia and fibula
M87.261Osteonecrosis due to previous trauma, right tibia
M87.262Osteonecrosis due to previous trauma, left tibia
M87.263Osteonecrosis due to previous trauma, unspecified tibia
M87.264Osteonecrosis due to previous trauma, right fibula
M87.265Osteonecrosis due to previous trauma, left fibula
M87.266Osteonecrosis due to previous trauma, unspecified fibula
M87.27Osteonecrosis due to previous trauma, ankle, foot and toes
M87.271Osteonecrosis due to previous trauma, right ankle
M87.272Osteonecrosis due to previous trauma, left ankle
M87.273Osteonecrosis due to previous trauma, unspecified ankle
M87.274Osteonecrosis due to previous trauma, right foot
M87.275Osteonecrosis due to previous trauma, left foot
M87.276Osteonecrosis due to previous trauma, unspecified foot
M87.277Osteonecrosis due to previous trauma, right toe(s)
M87.278Osteonecrosis due to previous trauma, left toe(s)
M87.279Osteonecrosis due to previous trauma, unspecified toe(s)
M87.28Osteonecrosis due to previous trauma, other site
M87.29Osteonecrosis due to previous trauma, multiple sites
M87.3Other secondary osteonecrosis
M87.30Other secondary osteonecrosis, unspecified bone
M87.31Other secondary osteonecrosis, shoulder
M87.311Other secondary osteonecrosis, right shoulder
M87.312Other secondary osteonecrosis, left shoulder
M87.319Other secondary osteonecrosis, unspecified shoulder
M87.32Other secondary osteonecrosis, humerus
M87.321Other secondary osteonecrosis, right humerus
M87.322Other secondary osteonecrosis, left humerus
M87.329Other secondary osteonecrosis, unspecified humerus
M87.33Other secondary osteonecrosis of radius, ulna and carpus
M87.331Other secondary osteonecrosis of right radius
M87.332Other secondary osteonecrosis of left radius
M87.333Other secondary osteonecrosis of unspecified radius
M87.334Other secondary osteonecrosis of right ulna
M87.335Other secondary osteonecrosis of left ulna
M87.336Other secondary osteonecrosis of unspecified ulna
M87.337Other secondary osteonecrosis of right carpus
M87.338Other secondary osteonecrosis of left carpus
M87.339Other secondary osteonecrosis of unspecified carpus
M87.34Other secondary osteonecrosis, hand and fingers
M87.341Other secondary osteonecrosis, right hand
M87.342Other secondary osteonecrosis, left hand
M87.343Other secondary osteonecrosis, unspecified hand
M87.344Other secondary osteonecrosis, right finger(s)
M87.345Other secondary osteonecrosis, left finger(s)
M87.346Other secondary osteonecrosis, unspecified finger(s)
M87.35Other secondary osteonecrosis, pelvis and femur
M87.350Other secondary osteonecrosis, pelvis
M87.351Other secondary osteonecrosis, right femur
M87.352Other secondary osteonecrosis, left femur
M87.353Other secondary osteonecrosis, unspecified femur
M87.36Other secondary osteonecrosis, tibia and fibula
M87.361Other secondary osteonecrosis, right tibia
M87.362Other secondary osteonecrosis, left tibia
M87.363Other secondary osteonecrosis, unspecified tibia
M87.364Other secondary osteonecrosis, right fibula
M87.365Other secondary osteonecrosis, left fibula
M87.366Other secondary osteonecrosis, unspecified fibula
M87.37Other secondary osteonecrosis, ankle and foot
M87.371Other secondary osteonecrosis, right ankle
M87.372Other secondary osteonecrosis, left ankle
M87.373Other secondary osteonecrosis, unspecified ankle
M87.374Other secondary osteonecrosis, right foot
M87.375Other secondary osteonecrosis, left foot
M87.376Other secondary osteonecrosis, unspecified foot
M87.377Other secondary osteonecrosis, right toe(s)
M87.378Other secondary osteonecrosis, left toe(s)
M87.379Other secondary osteonecrosis, unspecified toe(s)
M87.38Other secondary osteonecrosis, other site
M87.39Other secondary osteonecrosis, multiple sites
M87.8Other osteonecrosis
M87.80Other osteonecrosis, unspecified bone
M87.81Other osteonecrosis, shoulder
M87.811Other osteonecrosis, right shoulder
M87.812Other osteonecrosis, left shoulder
M87.819Other osteonecrosis, unspecified shoulder
M87.82Other osteonecrosis, humerus
M87.821Other osteonecrosis, right humerus
M87.822Other osteonecrosis, left humerus
M87.829Other osteonecrosis, unspecified humerus
M87.83Other osteonecrosis of radius, ulna and carpus
M87.831Other osteonecrosis of right radius
M87.832Other osteonecrosis of left radius
M87.833Other osteonecrosis of unspecified radius
M87.834Other osteonecrosis of right ulna
M87.835Other osteonecrosis of left ulna
M87.836Other osteonecrosis of unspecified ulna
M87.837Other osteonecrosis of right carpus
M87.838Other osteonecrosis of left carpus
M87.839Other osteonecrosis of unspecified carpus
M87.84Other osteonecrosis, hand and fingers
M87.841Other osteonecrosis, right hand
M87.842Other osteonecrosis, left hand
M87.843Other osteonecrosis, unspecified hand
M87.844Other osteonecrosis, right finger(s)
M87.845Other osteonecrosis, left finger(s)
M87.849Other osteonecrosis, unspecified finger(s)
M87.85Other osteonecrosis, pelvis and femur
M87.850Other osteonecrosis, pelvis
M87.851Other osteonecrosis, right femur
M87.852Other osteonecrosis, left femur
M87.859Other osteonecrosis, unspecified femur
M87.86Other osteonecrosis, tibia and fibula
M87.861Other osteonecrosis, right tibia
M87.862Other osteonecrosis, left tibia
M87.863Other osteonecrosis, unspecified tibia
M87.864Other osteonecrosis, right fibula
M87.865Other osteonecrosis, left fibula
M87.869Other osteonecrosis, unspecified fibula
M87.87Other osteonecrosis, ankle, foot and toes
M87.871Other osteonecrosis, right ankle
M87.872Other osteonecrosis, left ankle
M87.873Other osteonecrosis, unspecified ankle
M87.874Other osteonecrosis, right foot
M87.875Other osteonecrosis, left foot
M87.876Other osteonecrosis, unspecified foot
M87.877Other osteonecrosis, right toe(s)
M87.878Other osteonecrosis, left toe(s)
M87.879Other osteonecrosis, unspecified toe(s)
M87.88Other osteonecrosis, other site
M87.89Other osteonecrosis, multiple sites
M87.9Osteonecrosis, unspecified
M89.0Algoneurodystrophy
M89.00Algoneurodystrophy, unspecified site
M89.01Algoneurodystrophy, shoulder
M89.011Algoneurodystrophy, right shoulder
M89.012Algoneurodystrophy, left shoulder
M89.019Algoneurodystrophy, unspecified shoulder
M89.02Algoneurodystrophy, upper arm
M89.021Algoneurodystrophy, right upper arm
M89.022Algoneurodystrophy, left upper arm
M89.029Algoneurodystrophy, unspecified upper arm
M89.03Algoneurodystrophy, forearm
M89.031Algoneurodystrophy, right forearm
M89.032Algoneurodystrophy, left forearm
M89.039Algoneurodystrophy, unspecified forearm
M89.04Algoneurodystrophy, hand
M89.041Algoneurodystrophy, right hand
M89.042Algoneurodystrophy, left hand
M89.049Algoneurodystrophy, unspecified hand
M89.05Algoneurodystrophy, thigh
M89.051Algoneurodystrophy, right thigh
M89.052Algoneurodystrophy, left thigh
M89.059Algoneurodystrophy, unspecified thigh
M89.06Algoneurodystrophy, lower leg
M89.061Algoneurodystrophy, right lower leg
M89.062Algoneurodystrophy, left lower leg
M89.069Algoneurodystrophy, unspecified lower leg
M89.07Algoneurodystrophy, ankle and foot
M89.071Algoneurodystrophy, right ankle and foot
M89.072Algoneurodystrophy, left ankle and foot
M89.079Algoneurodystrophy, unspecified ankle and foot
M89.08Algoneurodystrophy, other site
M89.09Algoneurodystrophy, multiple sites
M89.1Physeal arrest
M89.12Physeal arrest, humerus
M89.121Complete physeal arrest, right proximal humerus
M89.122Complete physeal arrest, left proximal humerus
M89.123Partial physeal arrest, right proximal humerus
M89.124Partial physeal arrest, left proximal humerus
M89.125Complete physeal arrest, right distal humerus
M89.126Complete physeal arrest, left distal humerus
M89.127Partial physeal arrest, right distal humerus
M89.128Partial physeal arrest, left distal humerus
M89.129Physeal arrest, humerus, unspecified
M89.13Physeal arrest, forearm
M89.131Complete physeal arrest, right distal radius
M89.132Complete physeal arrest, left distal radius
M89.133Partial physeal arrest, right distal radius
M89.134Partial physeal arrest, left distal radius
M89.138Other physeal arrest of forearm
M89.139Physeal arrest, forearm, unspecified
M89.15Physeal arrest, femur
M89.151Complete physeal arrest, right proximal femur
M89.152Complete physeal arrest, left proximal femur
M89.153Partial physeal arrest, right proximal femur
M89.154Partial physeal arrest, left proximal femur
M89.155Complete physeal arrest, right distal femur
M89.156Complete physeal arrest, left distal femur
M89.157Partial physeal arrest, right distal femur
M89.158Partial physeal arrest, left distal femur
M89.159Physeal arrest, femur, unspecified
M89.16Physeal arrest, lower leg
M89.160Complete physeal arrest, right proximal tibia
M89.161Complete physeal arrest, left proximal tibia
M89.162Partial physeal arrest, right proximal tibia
M89.163Partial physeal arrest, left proximal tibia
M89.164Complete physeal arrest, right distal tibia
M89.165Complete physeal arrest, left distal tibia
M89.166Partial physeal arrest, right distal tibia
M89.167Partial physeal arrest, left distal tibia
M89.168Other physeal arrest of lower leg
M89.169Physeal arrest, lower leg, unspecified
M89.18Physeal arrest, other site
M89.2Other disorders of bone development and growth
M89.20Other disorders of bone development and growth, unspecified site
M89.21Other disorders of bone development and growth, shoulder
M89.211Other disorders of bone development and growth, right shoulder
M89.212Other disorders of bone development and growth, left shoulder
M89.219Other disorders of bone development and growth, unspecified shoulder
M89.22Other disorders of bone development and growth, humerus
M89.221Other disorders of bone development and growth, right humerus
M89.222Other disorders of bone development and growth, left humerus
M89.229Other disorders of bone development and growth, unspecified humerus
M89.23Other disorders of bone development and growth, ulna and radius
M89.231Other disorders of bone development and growth, right ulna
M89.232Other disorders of bone development and growth, left ulna
M89.233Other disorders of bone development and growth, right radius
M89.234Other disorders of bone development and growth, left radius
M89.239Other disorders of bone development and growth, unspecified ulna and radius
M89.24Other disorders of bone development and growth, hand
M89.241Other disorders of bone development and growth, right hand
M89.242Other disorders of bone development and growth, left hand
M89.249Other disorders of bone development and growth, unspecified hand
M89.25Other disorders of bone development and growth, femur
M89.251Other disorders of bone development and growth, right femur
M89.252Other disorders of bone development and growth, left femur
M89.259Other disorders of bone development and growth, unspecified femur
M89.26Other disorders of bone development and growth, tibia and fibula
M89.261Other disorders of bone development and growth, right tibia
M89.262Other disorders of bone development and growth, left tibia
M89.263Other disorders of bone development and growth, right fibula
M89.264Other disorders of bone development and growth, left fibula
M89.269Other disorders of bone development and growth, unspecified lower leg
M89.27Other disorders of bone development and growth, ankle and foot
M89.271Other disorders of bone development and growth, right ankle and foot
M89.272Other disorders of bone development and growth, left ankle and foot
M89.279Other disorders of bone development and growth, unspecified ankle and foot
M89.28Other disorders of bone development and growth, other site
M89.29Other disorders of bone development and growth, multiple sites
M89.3Hypertrophy of bone
M89.30Hypertrophy of bone, unspecified site
M89.31Hypertrophy of bone, shoulder
M89.311Hypertrophy of bone, right shoulder
M89.312Hypertrophy of bone, left shoulder
M89.319Hypertrophy of bone, unspecified shoulder
M89.32Hypertrophy of bone, humerus
M89.321Hypertrophy of bone, right humerus
M89.322Hypertrophy of bone, left humerus
M89.329Hypertrophy of bone, unspecified humerus
M89.33Hypertrophy of bone, ulna and radius
M89.331Hypertrophy of bone, right ulna
M89.332Hypertrophy of bone, left ulna
M89.333Hypertrophy of bone, right radius
M89.334Hypertrophy of bone, left radius
M89.339Hypertrophy of bone, unspecified ulna and radius
M89.34Hypertrophy of bone, hand
M89.341Hypertrophy of bone, right hand
M89.342Hypertrophy of bone, left hand
M89.349Hypertrophy of bone, unspecified hand
M89.35Hypertrophy of bone, femur
M89.351Hypertrophy of bone, right femur
M89.352Hypertrophy of bone, left femur
M89.359Hypertrophy of bone, unspecified femur
M89.36Hypertrophy of bone, tibia and fibula
M89.361Hypertrophy of bone, right tibia
M89.362Hypertrophy of bone, left tibia
M89.363Hypertrophy of bone, right fibula
M89.364Hypertrophy of bone, left fibula
M89.369Hypertrophy of bone, unspecified tibia and fibula
M89.37Hypertrophy of bone, ankle and foot
M89.371Hypertrophy of bone, right ankle and foot
M89.372Hypertrophy of bone, left ankle and foot
M89.379Hypertrophy of bone, unspecified ankle and foot
M89.38Hypertrophy of bone, other site
M89.39Hypertrophy of bone, multiple sites
M89.4Other hypertrophic osteoarthropathy
M89.40Other hypertrophic osteoarthropathy, unspecified site
M89.41Other hypertrophic osteoarthropathy, shoulder
M89.411Other hypertrophic osteoarthropathy, right shoulder
M89.412Other hypertrophic osteoarthropathy, left shoulder
M89.419Other hypertrophic osteoarthropathy, unspecified shoulder
M89.42Other hypertrophic osteoarthropathy, upper arm
M89.421Other hypertrophic osteoarthropathy, right upper arm
M89.422Other hypertrophic osteoarthropathy, left upper arm
M89.429Other hypertrophic osteoarthropathy, unspecified upper arm
M89.43Other hypertrophic osteoarthropathy, forearm
M89.431Other hypertrophic osteoarthropathy, right forearm
M89.432Other hypertrophic osteoarthropathy, left forearm
M89.439Other hypertrophic osteoarthropathy, unspecified forearm
M89.44Other hypertrophic osteoarthropathy, hand
M89.441Other hypertrophic osteoarthropathy, right hand
M89.442Other hypertrophic osteoarthropathy, left hand
M89.449Other hypertrophic osteoarthropathy, unspecified hand
M89.45Other hypertrophic osteoarthropathy, thigh
M89.451Other hypertrophic osteoarthropathy, right thigh
M89.452Other hypertrophic osteoarthropathy, left thigh
M89.459Other hypertrophic osteoarthropathy, unspecified thigh
M89.46Other hypertrophic osteoarthropathy, lower leg
M89.461Other hypertrophic osteoarthropathy, right lower leg
M89.462Other hypertrophic osteoarthropathy, left lower leg
M89.469Other hypertrophic osteoarthropathy, unspecified lower leg
M89.47Other hypertrophic osteoarthropathy, ankle and foot
M89.471Other hypertrophic osteoarthropathy, right ankle and foot
M89.472Other hypertrophic osteoarthropathy, left ankle and foot
M89.479Other hypertrophic osteoarthropathy, unspecified ankle and foot
M89.48Other hypertrophic osteoarthropathy, other site
M89.49Other hypertrophic osteoarthropathy, multiple sites
M89.5Osteolysis
M89.50Osteolysis, unspecified site
M89.51Osteolysis, shoulder
M89.511Osteolysis, right shoulder
M89.512Osteolysis, left shoulder
M89.519Osteolysis, unspecified shoulder
M89.52Osteolysis, upper arm
M89.521Osteolysis, right upper arm
M89.522Osteolysis, left upper arm
M89.529Osteolysis, unspecified upper arm
M89.53Osteolysis, forearm
M89.531Osteolysis, right forearm
M89.532Osteolysis, left forearm
M89.539Osteolysis, unspecified forearm
M89.54Osteolysis, hand
M89.541Osteolysis, right hand
M89.542Osteolysis, left hand
M89.549Osteolysis, unspecified hand
M89.55Osteolysis, thigh
M89.551Osteolysis, right thigh
M89.552Osteolysis, left thigh
M89.559Osteolysis, unspecified thigh
M89.56Osteolysis, lower leg
M89.561Osteolysis, right lower leg
M89.562Osteolysis, left lower leg
M89.569Osteolysis, unspecified lower leg
M89.57Osteolysis, ankle and foot
M89.571Osteolysis, right ankle and foot
M89.572Osteolysis, left ankle and foot
M89.579Osteolysis, unspecified ankle and foot
M89.58Osteolysis, other site
M89.59Osteolysis, multiple sites
M89.6Osteopathy after poliomyelitis
M89.60Osteopathy after poliomyelitis, unspecified site
M89.61Osteopathy after poliomyelitis, shoulder
M89.611Osteopathy after poliomyelitis, right shoulder
M89.612Osteopathy after poliomyelitis, left shoulder
M89.619Osteopathy after poliomyelitis, unspecified shoulder
M89.62Osteopathy after poliomyelitis, upper arm
M89.621Osteopathy after poliomyelitis, right upper arm
M89.622Osteopathy after poliomyelitis, left upper arm
M89.629Osteopathy after poliomyelitis, unspecified upper arm
M89.63Osteopathy after poliomyelitis, forearm
M89.631Osteopathy after poliomyelitis, right forearm
M89.632Osteopathy after poliomyelitis, left forearm
M89.639Osteopathy after poliomyelitis, unspecified forearm
M89.64Osteopathy after poliomyelitis, hand
M89.641Osteopathy after poliomyelitis, right hand
M89.642Osteopathy after poliomyelitis, left hand
M89.649Osteopathy after poliomyelitis, unspecified hand
M89.65Osteopathy after poliomyelitis, thigh
M89.651Osteopathy after poliomyelitis, right thigh
M89.652Osteopathy after poliomyelitis, left thigh
M89.659Osteopathy after poliomyelitis, unspecified thigh
M89.66Osteopathy after poliomyelitis, lower leg
M89.661Osteopathy after poliomyelitis, right lower leg
M89.662Osteopathy after poliomyelitis, left lower leg
M89.669Osteopathy after poliomyelitis, unspecified lower leg
M89.67Osteopathy after poliomyelitis, ankle and foot
M89.671Osteopathy after poliomyelitis, right ankle and foot
M89.672Osteopathy after poliomyelitis, left ankle and foot
M89.679Osteopathy after poliomyelitis, unspecified ankle and foot
M89.68Osteopathy after poliomyelitis, other site
M89.69Osteopathy after poliomyelitis, multiple sites
M89.7Major osseous defect
M89.70Major osseous defect, unspecified site
M89.71Major osseous defect, shoulder region
M89.711Major osseous defect, right shoulder region
M89.712Major osseous defect, left shoulder region
M89.719Major osseous defect, unspecified shoulder region
M89.72Major osseous defect, humerus
M89.721Major osseous defect, right humerus
M89.722Major osseous defect, left humerus
M89.729Major osseous defect, unspecified humerus
M89.73Major osseous defect, forearm
M89.731Major osseous defect, right forearm
M89.732Major osseous defect, left forearm
M89.739Major osseous defect, unspecified forearm
M89.74Major osseous defect, hand
M89.741Major osseous defect, right hand
M89.742Major osseous defect, left hand
M89.749Major osseous defect, unspecified hand
M89.75Major osseous defect, pelvic region and thigh
M89.751Major osseous defect, right pelvic region and thigh
M89.752Major osseous defect, left pelvic region and thigh
M89.759Major osseous defect, unspecified pelvic region and thigh
M89.76Major osseous defect, lower leg
M89.761Major osseous defect, right lower leg
M89.762Major osseous defect, left lower leg
M89.769Major osseous defect, unspecified lower leg
M89.77Major osseous defect, ankle and foot
M89.771Major osseous defect, right ankle and foot
M89.772Major osseous defect, left ankle and foot
M89.779Major osseous defect, unspecified ankle and foot
M89.78Major osseous defect, other site
M89.79Major osseous defect, multiple sites
M89.8Other specified disorders of bone
M89.8XOther specified disorders of bone
M89.8X0Other specified disorders of bone, multiple sites
M89.8X1Other specified disorders of bone, shoulder
M89.8X2Other specified disorders of bone, upper arm
M89.8X3Other specified disorders of bone, forearm
M89.8X4Other specified disorders of bone, hand
M89.8X5Other specified disorders of bone, thigh
M89.8X6Other specified disorders of bone, lower leg
M89.8X7Other specified disorders of bone, ankle and foot
M89.8X8Other specified disorders of bone, other site
M89.8X9Other specified disorders of bone, unspecified site
M89.9Disorder of bone, unspecified
O26.5Maternal hypotension syndrome
O26.53Maternal hypotension syndrome, third trimester
Q78.0Osteogenesis imperfecta
Q78.1Polyostotic fibrous dysplasia
Q78.2Osteopetrosis
Q78.3Progressive diaphyseal dysplasia
Q78.4Enchondromatosis
Q78.5Metaphyseal dysplasia
Q78.6Multiple congenital exostoses
Q78.8Other specified osteochondrodysplasias
Q78.9Osteochondrodysplasia, unspecified
Z13.7Encounter for screening for genetic and chromosomal anomalies
Z13.79Encounter for other screening for genetic and chromosomal anomalies
Z36.0Encounter for antenatal screening for chromosomal anomalies
Z82.7Family history of congenital malformations, deformations and chromosomal abnormalities

References